Pueblo is located on Interstate Highway 25, about 45 miles south of Colorado Springs, 120 miles south of Denver, and 100 miles north of the New Mexico border. US Route 50 connects Pueblo to points east and west.
Pueblo is the heart of the Pueblo Metropolitan Statistical Area, totaling over 160,000 people and an important part of the Front Range Urban Corridor. As of 2014, Pueblo is the primary city of the Pueblo–Cañon City combined statistical area (CSA) totaling approximately 208,000 people, making it the 134th largest in the nation. Pueblo is situated at the confluence of the Arkansas River and Fountain Creek, 112 miles (180 km) south of the Colorado State Capitol in Denver. The area is considered semi-arid desert land, with approximately 12 inches (304. 80 mm) of precipitation annually. With its location in the "Banana Belt", Pueblo tends to get less snow than the other major cities in Colorado. Pueblo is one of the largest steel-producing cities in the United States, for which reason Pueblo is referred to as the "Steel City". The Historic Arkansas River Project (HARP) is a river walk in the Union Avenue Historic Commercial District, and shows the history of the devastating Pueblo Flood of 1921.